N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-[(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL]-D-LYSINE - Names and Identifiers
Name | Fmoc-D-Lys(Dde)-OH
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Synonyms | Fmoc-D-Lys(Dde)-OH FMOC-D-LYS(DDE)-OH (9H-Fluoren-9-yl)MethOxy]Carbonyl D-Lys(Dde)-OH N-ALPHA-FMOC-N-EPSILON-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-D-LYSINE N6-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-lysine D-Lysine, N6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]- N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-D-LYSINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-[(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL]-D-LYSINE (2R)-6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
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CAS | 333973-51-6
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N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-[(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL]-D-LYSINE - Physico-chemical Properties
Molecular Formula | C31H36N2O6
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Molar Mass | 532.63 |
Density | 1.222±0.06 g/cm3(Predicted) |
Melting Point | ~80°C (dec.) |
Boling Point | 750.1±60.0 °C(Predicted) |
pKa | 3.88±0.21(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-[(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL]-D-LYSINE - Introduction
Fmoc-D-Lys(Dde)-OH is an amino acid derivative with the following properties:
Nature:
1. Chemical formula: C32H37FN6O6
2. Molecular Weight: 633.67g/mol
3. Appearance: solid, white to light yellow crystalline
4. Solubility: It is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM).
Use:
1. Biochemical research: Fmoc-D-Lys(Dde)-OH is usually used as an amino acid in the synthesis of peptides and proteins.
2. Drug development: It also has certain applications in pharmaceutical chemistry, and can be used to design and synthesize compounds with specific biological activities.
Method:
The synthesis of Fmoc-D-Lys(Dde)-OH is generally divided into two steps. First, a Fmoc protecting group was introduced on the amino group of L-lysine by synthetic chemistry. Then, a Dde protecting group is introduced into the ε-amino group to form Fmoc-D-Lys(Dde)-OH.
Safety Information:
1. Fmoc-D-Lys(Dde)-OH has no obvious toxicity under normal operating conditions.
2. During use, avoid inhalation or skin contact. Appropriate personal protective measures, such as wearing gloves, protective clothing and masks, are required.
3. When handling Fmoc-D-Lys(Dde)-OH, follow the laboratory safety procedures and follow its relevant safety information.
Last Update:2024-04-09 21:01:54